Baking tilapia at 375°F (190°C) is a quick and easy way to cook this versatile fish. The cooking time will depend on the thickness of the fillets, but usually takes 8 to 12 minutes. To ensure perfectly cooked tilapia, remove it from the oven when it reaches an internal temperature of 145°F (63°C). Baking tilapia at 375°F will result in a juicy, flaky, and delicious fish that can be served with various sides or topped with your favorite sauce.
Is Good To Cook Tilapia At 375?
Cooking tilapia at 375°F (190°C) is ideal for a fast and tasty meal. It results in a juicy and flavorful fish that is versatile and easy to prepare. The cooking time for tilapia at this temperature varies depending on the thickness of the fillets, but typically takes 8 to 12 minutes. Remember to monitor the internal temperature of the fish and remove it from the oven when it reaches 145°F (63°C) for optimal results.
How To Prepare Tilapia Before Baking?
- Rinse the tilapia fillets and pat them dry with paper towels.
- Season the fillets with salt, pepper, and any desired herbs or spices.
- Lightly oil a baking dish and place the fillets in the dish.
- Bake the tilapia at 375°F for 8-12 minutes, or until the internal temperature reaches 145°F.
- Let the fish rest for a few minutes before serving with sides such as roasted vegetables, salad, or rice.
Note: Tilapia can also be wrapped in foil or parchment paper for a moister texture.

Baked Tilapia Ingredients:
- 4 tilapia fillets
- Salt and pepper to taste
- 2 tablespoons olive oil
- 2 lemons, sliced
- 2 cloves of garlic, minced
- 1 teaspoon dried thyme
- 1 teaspoon dried basil
How Long To Bake Tilapia At 375°F in The Oven
- Preheat the oven to 375°F (190°C).
- Rinse the tilapia fillets under cold running water and pat them dry with paper towels.
- Season the fillets with salt and pepper.
- In a baking dish, combine the olive oil, lemon slices, garlic, thyme, and basil. Place the seasoned tilapia fillets in the dish, making sure they are spaced apart.
- Bake the tilapia in the preheated oven for 8 to 12 minutes, or until the internal temperature of the fish reaches 145°F (63°C).
- Remove the baking dish from the oven and let the tilapia rest for a few minutes before serving.
- Serve the tilapia with a squeeze of lemon juice, a sprinkle of herbs, and your choice of side dishes. Enjoy!
How Long To Cook Tilapia At 375
At 375°F (190°C), tilapia takes between 8 and 12 minutes to cook, depending on how thick the fillets are. Before taking the fish out of the oven, you should use a meat thermometer to check the temperature inside the fish and make sure it reaches 145°F (63°C). Overcooking fish can make it tough and dry, while undercooking it can make you sick.
How Long To Cook Tilapia At 375 In The Air Fryer
To cook tilapia in an air fryer, set the temperature to 375°F (190°C) and cook the fillets for 8 to 10 minutes. Use a meat thermometer to ensure the internal temperature of the fish reaches 145°F (63°C) before removing it from the air fryer.

Can I Cook Tilapia On Crock Pot
Slow cooking tilapia in a Crock-Pot is not recommended as it can result in mushy and flavorless fish. It’s best to use high-heat cooking methods such as baking, grilling, or pan-frying for tilapia. If you want to use a slow cooker, it’s better to choose a meatier fish like salmon or cod or cook tilapia in a sauce and finish it in the oven or on the stovetop.
How Long To Cook Tilapia In The Pan-Fry/Stovetop:
To pan-fry tilapia, cook it for 4 to 6 minutes per side at medium-high heat, depending on the thickness of the fillets. Use a meat thermometer to check the internal temperature of the fish, which should reach 145°F (63°C) before removing it from the pan. Avoid overcooking the fish, as this can make it dry and tough. After cooking, let the fish rest for a few minutes before serving to retain its texture and flavor.

How Long To Cook A Frozen Tilapia At 375:
To cook frozen tilapia in the oven, preheat to 375°F (190°C) and bake for 20-25 minutes. Ensure the fish reaches an internal temperature of 145°F (63°C) before removing. Defrost the tilapia completely first, either in the fridge or cold water for 30 minutes. Place the fish with enough space to circulate heat and season with olive oil, lemon juice, and your favorite spices.
What Temperature Should A Tilapia Be Cooked To?
To ensure the safety of tilapia, it should be cooked to an internal temperature of 145°F (63°C). To prevent dry and tough fish, avoid overcooking. A meat thermometer can be used to check the temperature in the thickest part without touching the bone.
Should Tilapia Be Covered While Baking?
When baking tilapia, covering the dish can help the fish cook evenly and retain moisture, which is useful when baking it in a sauce or topping. However, uncovering the dish for the last few minutes of baking can create a crispy crust. Whether to cover the tilapia or not depends on personal preference and desired texture.
You can determine if tilapia is fully cooked by using a meat thermometer or the “flakiness test.” Check the internal temperature with a thermometer and make sure it reaches 145°F (63°C).
Alternatively, gently press the fish with a fork to see if it flakes easily. Overcooking tilapia can make it dry and tough, so monitor it closely to avoid overcooking.
FAQ Section
How long does it take to cook tilapia at 400 degrees?
To bake tilapia, preheat the oven to 400°F and line a baking sheet with parchment paper. Season the tilapia fillets to your preference and bake for 6-8 minutes.
How do you avoid overcooking tilapia?
Prevent overcooked tilapia by using a meat thermometer to monitor the internal temperature. Remove the fish from the heat source when it reaches 145°F (63°C).
Can you bake tilapia at a different temperature than 375°F?
A different baking temperature can be used for tilapia, but it is recommended to adjust the cooking time accordingly. Starting with a baking temperature of 375°F is a good guideline.
How long does it take to cook tilapia at 350 degrees?
Baking tilapia at 350°F takes about 10 to 15 minutes, depending on the thickness of the fish. To ensure that the tilapia is fully cooked, it’s best to use a food thermometer and remove the fish from the oven when the internal temperature reaches 145°F.
How To Store Cooked Tilapia?
To store cooked tilapia, place it in an airtight container in the refrigerator for up to 3-4 days. To prevent air exposure and limit moisture loss, wrap it tightly with aluminum foil or plastic wrap. Store the container in the coldest part of your refrigerator, typically the back near the bottom.